Our Automated Parallel Synthesizers enable the rapid and efficient generation of large combinatorial libraries by running multiple chemical reactions simultaneously under controlled conditions. By integrating a split-and-pool strategy similar to that in DELs, we achieve vast molecular diversity while maintaining precise control over reaction pathways and compound tracking. This approach accelerates synthesis cycles, increases throughput, and ensures that our libraries capture broad regions of chemical space.

Our Advanced Synthesis Systems provide the tools to perform a broad range of chemical transformations beyond the constraints of DNA-encoded library chemistry. Equipped with automated parallel synthesizers and microwave-assisted reactors, these instruments enable rapid optimization, high-throughput combinatorial synthesis, and efficient execution of reactions such as amide formation, reductive amination, click chemistry, and palladium-catalyzed cross-couplings. These systems, the lab can generate highly diverse molecular libraries at scale, exploring chemical space that traditional DEL methods cannot reach.

Our Automated Liquid Handling Robots streamline the synthesis and management of combinatorial libraries by precisely dispensing reagents, performing split-and-pool operations, and arraying compounds at scale. By automating these repetitive and high-throughput tasks, we reduce variability, improve reproducibility, and accelerate the overall workflow from synthesis to screening. This technology ensures that large, diverse libraries can be generated efficiently while maintaining strict control over reaction conditions and compound tracking.

Our SCL Design Tools provide a next-generation alternative to DNA-encoded libraries by eliminating the steric and chemical constraints imposed by DNA tags. Instead of embedding artificial markers, we harness spectral signatures decoded through advanced AI analytics and the high-resolution power of mass spectrometry. Our SCL Design Tools allow precise identification and tracking of molecules in combinatorial libraries without altering their properties, expanding chemical diversity, preserving fidelity, and accelerating the transition from synthesis to biological screening into regions of chemical space inaccessible to traditional encoding methods.